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Dual-modality Breast Imaging

Principal Investigator: Tania Douglas

A number of breast cancer indicators such as non-calcified masses can be missed by mammography. Although ultrasound does not have the spatial resolution of X-rays, it is able to differentiate tissues of different densities and has been used as an adjunct to X-ray mammography for more than fifty years. Diagnostic breast ultrasound now plays a vitally important role in the detection of cancer. We are collaborating with a local Cape Town based company, CapeRay Medical (Pty) Ltd, which has developed an imaging platform called that integrates digital mammography and automated breast ultrasound into a single instrument. The X-ray imaging component of the dual-modality system is an outflow of our work with Lodox Systems on slot-scanning X-ray imaging; CapeRay was established in 2010 to further develop and commercialise a slot-scanning mammography system resulting from a project under the collaboration with Lodox Systems.

The main objective of this research is to perform simultaneous mammography and ultrasound imaging of the breast using a single system and determine whether this improves the accuracy of diagnosis over using mammography alone. For this purpose, CapeRay’s dual-modality imaging system is being evaluated.

CapeRay's weekly blog provides interesting reading on breast cancer diagnostic technologies and related matters.

Journal publications

  • CL Vaughan, TS Douglas, Q Said-Hartley, RV Baasch, JA Boonzaier, BrC Goemans, J Harverson, MW Mingay, S Omar, RV Smith, NC Venter, HS Wilson. Testing a dual-modality system that combines full-field digital mammography and automated breast ultrasound. Clinical Imaging, DOI:10.1016/j.clinimag.2015.11.024.